Description

This episode centres around an article recently published in the Journal of Hepatology, presenting a new treatment algorithm positioned as an evolution of the BCLC system and aimed at addressing its limitations in the staging and therapy hierarchy for HCC. This discussion covers the implications of this fresh approach in the management of HCC patients, challenging the standard paradigm.

Faculty

• Bruno Sangro (Moderator)
• Umberto Cillo (Faculty) 
• Helen Reeves (Faculty)
• María Reig (Faculty)

This EASL Studio is supported by AstraZeneca. EASL has received no input from AstraZeneca with regards to the content of this programme.

Related episodes

• EASL Studio S5E13: Basics in decision-making for liver cancer treatment
• EASL Studio from EASL Congress 2023: Highlights of the liver cancer research at EASL Congress 2023
• EASL Studio S4E16: Highlights from the EASL Liver Cancer Summit 2023
• EASL Studio S4 Special Edition 1: A new strategy for liver cancer screening: EASL Policy Statement on risk-based surveillance
• EASL Studio S3E16: Liver cancer in 2022: Wrap-up & outlook
• EASL Studio S3E8: Transplanting patients with cancer – Is there a limit?
• EASL Studio S2E15: JHEP Live on the best animal model for HCC – Lost in translation?

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

Description

The definition of cACLD is now strongly linked to care and research outcomes such as non invasive diagnosis, reversibility and prevention of decompensation. Thus, what space is left for the use of the old term cirrhosis in clinical practice and research?

Faculty

• Paolo Angeli (Moderator)
• Guadalupe Garcia-Tsao (Faculty)
• Valérie Paradis (Faculty)
• Thomas Reiberger (Faculty)

Related episodes

• EASL Studio S5E5: JHEP Live: the new nomenclature for SLD: a multidisciplinary evaluation and approach
• EASL Studio from EASL Congress 2023: Steatotic liver disease global consensus to change nomenclature
• EASL Studio S4E4: JHEP Live: Is the term ‘decompensated cirrhosis’ outdated?

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

Description

In this episode, the faculty review the evidence base for ammonia measurement in patients with cirrhosis, exploring whether hyperammonaemia is indicative of a poor prognosis and if erroneous measurements correlate with the efficacy of ammonia-lowering therapies. The debate also extends to the use of ammonia as a potential endpoint in randomised controlled trials for hepatic encephalopathy drugs.

Faculty

• Debbie Shawcross (Moderator)
• Rajiv Jalan (Faculty)
• Sara Montagnese (Faculty)
• Elliot Tapper (Faculty)

This EASL Studio episode is organised in collaboration with the International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN).

Related episodes

• EASL Studio S5E11: Statins in cirrhosis: The window hypothesis again, or just a closed window?
• EASL Studio from EASL Congress 2023: Liver cirrhosis in 2023: Unmet needs and how to address them
• EASL Studio S4E17: Albumin in Cirrhosis: For all, some, or none?
• EASL Studio S3E12: Meeting the challenge of antimicrobial resistance (AMR) in cirrhosis: the invisible threat that lies within
• EASL Studio S2E6: Should anticoagulants be given to patients with cirrhosis to improve outcome?
• EASL Studio S2E4: Betablockers in cirrhosis: Has Baveno consensus gone too far?

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

Description

This episode treats of the Hepahealth II study, which aimed at estimating the impact of policy interventions targeting alcohol and obesity on the incidence of chronic liver disease and primary liver cancer in three European countries. Join our experts in their discussion of this study and of its conclusions.

Faculty

• Patrizia Burra (Moderator)
• Maria Buti (Faculty)
• Peter Jepsen (Faculty)
• Shira Zelber-Sagi (Faculty)

Related episodes

• EASL Studio S6E1: Do we solve MASLD by treating obesity?
• EASL Studio from EASL Congress 2023: The battle to reduce alcohol harms… EASL’s new policy
• EASL Studio S4E8: The central role of alcohol and food policies on liver health
• EASL Studio S2E2: Fats or carbs, who is the real villain?

ℹ️ Please click here to access the podcast version of this EASL Studio episode.