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EASL Policy Dialogues S2 E4: World Hepatitis Day – Spotlight on Hepatitis D

Description

This episode focuses on Hepatitis D (HDV), which is less common than hepatitis B or C but is a serious disease that often affects underprivileged and vulnerable populations. HDV has long been neglected and even though it is a highly aggressive viral hepatitis which can rapidly progress to cirrhosis and liver cancer, it remains under-recognised, underestimated, and under-treated. What is the status of Hepatitis D elimination globally and what challenges do we still face? Which strategies would be best deployed against Hepatitis D? How can lessons learned about Hepatitis C elimination be applied to Hepatitis Delta?

The EASL Policy Dialogues are supported by CymaBay, Echosens, Grifols and Novo Nordisk. CymaBay, Echosens, Grifols and Novo Nordisk have had no input into the content of the EASL Policy Dialogues.

 

Speakers

 
Maurizia Brunetto

Maurizia R. Brunetto is Director of the Integrated Care Department of Medical Specialties and of the Liver Unit and Laboratory of Molecular Genetics and Pathology of Hepatitis Viruses of Pisa University Hospital.  Her research activity has been focused on the study of the pathogenetic implications of hepatitis virus infection, on the analysis of factors influencing the progression of chronic hepatitis to cirrhosis and hepatocellular carcinoma and on the treatment optimization. She did seminal work in the clinic-pathologic characterization of the HBeAg negative chronic hepatitis B with the identification of Pre-core mutant and demonstrated  the clinical usefulness of HBsAg serum levels measurement in the monitoring of antiviral      therapy and identification of HBeAg negative infection with the definition of the clinical cut-off, currently suggested by the international guidelines.

Lindsey Hiebert

Lindsey Hiebert is the Associate Director of the Coalition for Global Hepatitis Elimination. The Coalition is based at the Task Force for Global Health, an international NGO in Atlanta, United States. At the Coalition, Lindsey supports initiatives related to technical assistance, operational research, advocacy, and policy to advance hepatitis B and C elimination globally.

 

 

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EASL Policy Dialogues S2 E5: Rare but not forgotten – The challenges of living with PBC

Description

This episode released on the occasion of Primary Biliary Cholangitis (PBC) Awareness Day (11 Septembre) focuses on the disease of PBC, its demographic, symptoms, treatments options and patient’s needs. What is primary biliary cholangitis, what is the general demographic of those affected and when are most patients diagnosed? What role should patients and patient groups have in research? What challenges do PBC patients face in healthcare settings and more generally?

The EASL Policy Dialogues are supported by CymaBay, Echosens, Grifols and Novo Nordisk. CymaBay, Echosens, Grifols and Novo Nordisk have had no input into the content of the EASL Policy Dialogues.

 

Speakers

 
Jessica

Dr Jess Dyson is a consultant hepatologist at the Freeman Hospital in Newcastle with a combined role as an NHS hepatologist with a major interest in clinical research based at Newcastle University. She leads the clinical service in Newcastle for patients with autoimmune liver disease including running the regional network for delivery of 2nd-line therapies in high risk primary biliary cholangitis. She is principal investigator for the UK national study for patients with autoimmune hepatitis that focuses on improving therapy for patients (UK-AIH) and a co-author on the national guidelines for primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis. She completed her PhD in 2019 investigating potential environmental risk factors related to autoimmune liver disease.

Robert Mitchel

Robert Mitchell-Thain is Chief Executive Officer at the PBC Foundation and Chair of Paediatric and Rare Liver Diseases Council at the Global Liver Institute. Mitchell-Thain is a fierce patient advocate with over 20 years of international experience. A NAFLD patient himself, his main focus has been cholestatic liver disease. A member of numerous collaborative committees, lead and co-author on several patient-centric abstracts, co-author and reviewer of clinical guidelines and journal articles, he is known for challenging dogma and for a progressive approach to finding solutions in a patient-centred way, pursuing the best for all stakeholders within the community.

 

 

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EASL Policy Dialogues S2 E6: Diagnosing Steatotic Liver Disease – Challenges and opportunities

Description

This episode focuses on Steatotic Liver Disease (SLD). In 2023, EASL officially launched a global coalition, the Healthy Livers Healthy Lives, which brings together the four main professional liver societies, and aims to raise awareness on SLD. Discover what the coalition has achieved so far and its ultimate goal. The key issue of diagnostics for SLD and stratification pathways is being thoroughly discussed. What is the landscape of diagnostics for SLD? How non-invasive tests are being used in practice and what’s the situation around stratification pathways?

The EASL Policy Dialogues are supported by CymaBay, Echosens, Grifols and Novo Nordisk. CymaBay, Echosens, Grifols and Novo Nordisk have had no input into the content of the EASL Policy Dialogues.

 

Speakers

 
Jeffrey Lazarus

Jeffrey V. Lazarus (Ph.D., MIH, MA) is a Member of the EASL Policy and Public Health Committee. He holds positions as an associate research professor at the Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, where he leads the health systems research team, as Associate Professor at the Faculty of Medicine, University of Barcelona, Spain and as a senior scholar at the CUNY Graduate School of Public Health and Policy in New York City. His decade-long career as health systems, HIV, and viral hepatitis expert at WHO Europe was followed by three years (2009-2012) as a senior specialist at the Global Fund to Fight AIDS, Tuberculosis, and Malaria, three years as director of Health Systems Global (2012-15) then board chair of the foundation AFEW International (2015-18). Prof Lazarus is now Vice-Chairman of the board of the EASL International Liver Foundation, where he developed the micro-elimination approach to HCV elimination. He is also a member of the INHSU international education committee and co-chair of the HIV Outcomes Beyond Viral Suppression coalition. He is the author of more than 300 publications and his current scientific work includes leading the Hep C Free Baleares, HBV COMSAVA, and Copenhagen T'n'T studies, and the Global COVID-19 consensus statement on ending the pandemic. He is a core member of The Lancet GastroHep Commission on Viral Hepatitis, a co-author of the Lancet COVID-19 commission and a commissioner of the EASL-Lancet European Liver Commission and The Lancet-IAPAC HIV Commission. At AME/VE he is chair of the NAFLD models of care workshop, on the organizing committee of COLDA, and on the scientific committee of IVHEM.

Maja Thiele

Prof. Maja Thiele works to reduce morbidity and mortality from alcohol-related liver disease, for the benefit of an otherwise stigmatized patient group. Her research centers on the development and validation of diagnostic and prognostic biomarkers, with a particular focus on early disease detection, cost-effective referral pathways and omics technologies. Elastography expert contributor to EASL Clinical Practice Guidance, the BAVENO VII consensus statement, AASLD clinical guidance, WFUMB guideline, and The Lancet Commission on liver disease in primary care. Partner in the European research consortia GALAXY, LiverScreen, LIVERAIM, MicrobPredict and SALVE.

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EASL Policy Dialogues S2 E7: Inequality in liver care – Identifying and addressing disparities

Description

This episode focuses on liver cancer disparities in Europe. Liver cancer incidence disproportionately affects marginalized groups and deaths from liver cancer have continued to increase over the last decades. This episode addresses gaps in care, causes for inequities, and actions being taken at the EU level to improve liver cancer prevention.

The EASL Policy Dialogues are supported by CymaBay, Echosens, Grifols and Novo Nordisk. CymaBay, Echosens, Grifols and Novo Nordisk have had no input into the content of the EASL Policy Dialogues.

 

Speakers

 
Josep Llovet

Josep M. Llovet, MD, PhD is Professor of Medicine – Hepatic Oncology at University of Barcelona, Group leader and Professor of Research-ICREA in the Liver Unit, IDIBAPS-Hospital Clinic and Director of the Liver Cancer Program and Professor of Medicine at the Icahn School of Medicine at Mount Sinai, NY. He has devoted his career to the pathogenesis and treatment of liver cancer, publishing ~ 350 articles (~ 136,049 citations, h index: 134) and leading ~100 projects. He has been nominated as global Top-1% cited researcher (2014 to 2022) and nominated Editor in Chief of JHEP Reports (2024-29).

Richard Price

Richard Price is Head of Policy at European Cancer Organisation (ECO). He is a public policy professional with extensive experience in the healthcare and pharmaceutical sectors working as a policy manager in EU Affairs at ECO, policy and advocacy officer at the European Association of Hospital Pharmacists, and as policy advisor to the Pharmaceutical Society of Northern Ireland.

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EASL Policy Dialogues S2 E8: The political battle to reduce harms caused by alcohol

Description

The Awareness Week on Alcohol Related Harm (AWARH) serves to raise awareness for the incredibly high levels of alcohol consumption in Europe. AWARH week is designed to showcase policies that can be implemented at the EU and national levels to reduce population-level alcohol consumption. In this episode, Professor Nick Sheron, a clinical hepatologist, and Florence Berteletti, a public policy professional come together to discuss challenges in implementing alcohol policies and current initiatives taking place in Europe to address those obstacles.

The EASL Policy Dialogues are supported by CymaBay, Echosens, Grifols and Novo Nordisk. CymaBay, Echosens, Grifols and Novo Nordisk have had no input into the content of the EASL Policy Dialogues.

 

Speakers

 
Nick Sheron

Nick Sheron is an academic clinical hepatologist at University of Southampton and runs the liver unit at Southampton General Hospital. He is also actively involved in a clinically based programme of research in various aspects of alcohol-related problems. Together with Ian Gilmore, President of the Royal College of Physicians, he co-founded the Alcohol Health Alliance UK, an umbrella body bring together 27 different organisations including Royal Colleges, NGOs and charities with the aim of lobbying for evidence-based policies to reduce alcohol-related harm in the UK. He is also a founder member of the European Union Alcohol Forum, a member of the European Union Alcohol Marketing Taskforce and two bodies of which have been set up by the European Commission in order to take forward the EU Alcohol Strategy.

Florence Berteletti

Florence Berteletti has over 20 years of international policy and advocacy experience in diverse fields including fiscal policies for health, tobacco control, alcohol related harm and culture policy. Florence Berteletti was appointed Secretary General of Eurocare in August 2021. Between 2018 and August 2021, Florence was Advocacy Director at the World Heart Federation where she was responsible for leading WHF’s global policy and advocacy and led dossiers related to Front of Pack Labelling, Fiscal Policies for Health, Rheumatic Heart Diseases and Air pollution, to name just a few. Before WHF, Florence was Director of the Smoke Free Partnership (SFP), an alliance of 52 civil society organisations dedicated to the implementation of the WH Framework Convention on Tobacco Control (FCTC).

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EASL Studio S5 E13: Basics in decision-making for liver cancer treatment

Description

With cases of hepatocellular carcinoma on the rise and representing the end stage of many chronic liver diseases, the treatment of liver cancer has become one of the most dynamic areas in hepatology. The focus of this episode is on answering practical clinical questions, examining trial data, and sharing clinical insights that may be useful for decision-making in daily clinical practice.

Faculty

  • Tom Lüdde (Moderator)
  • Christoph Roderburg (Faculty)
  • Anna Saborowski (Faculty)
  • Arndt Vogel (Faculty)

This EASL Studio is supported by AstraZeneca and Eisai. EASL has received no input from AstraZeneca or Eisai with regards to the content of this programme.

Related episodes

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

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Liver Tumours
EASL Studio Podcast S5 E13: Basics in decision-making for liver cancer treatment

EASL Studio Podcast S5 E13: Basics in decision-making for liver cancer treatment

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EASL Studio S5 E12: PSC and AIH overlap syndrome: does it actually exist?

Description

This episode explores key aspects of intriguing intersection of autoimmune liver diseases, such as their distinctive presentations in childhood and adulthood and the influence of inflammatory bowel disease on liver disease phenotypes. The speakers also examines the benefits and risks associated with immunosuppressive treatments in managing these complex conditions.

Faculty

  • Palak Trivedi (Moderator)
  • Amanda Ricciuto (Faculty)
  • Marianne Samyn (Faculty)
  • Christoph Schramm (Faculty)

This EASL Studio is supported by Chemomab Therapeutics. EASL has received no input from Chemomab Therapeutics with regards to the content of this programme.

Related episodes

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

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Immune-Mediated and Cholestatic Diseases
EASL Studio Podcast S5 E12: PSC and AIH overlap syndrome: does it actually exist?

EASL Studio Podcast S5 E12: PSC and AIH overlap syndrome: does it actually exist?

Podcasts
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EASL Studio S5 E11: Statins in cirrhosis: The window hypothesis again, or just a closed window?

Description

The treatment of liver cirrhosis – currently based on symptomatic management of complications – has barely changed in last 20 years. In this episode, the experts discuss the use of statins, for which there is growing body of evidence of their beneficial effects in patients suffering with cirrhosis.

Faculty

  • Thomas Reiberger (Moderator)
  • Juan Gonzalez-Abraldes (Faculty)
  • Elisa Pose (Faculty)
  • Jonel Trebicka (Faculty)

This EASL Studio is supported by Boehringer Ingelheim. EASL has received no input from Boehringer Ingelheim with regards to the content of this programme.

Related episodes

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

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Immune-Mediated and Cholestatic Diseases
Quiz: Which of the following constitute a good phenotypic prognostic factor in patients with primary sclerosing cholangitis?

Quiz: Which of the following constitute a good phenotypic prognostic factor in patients with primary sclerosing cholangitis?

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Cirrhosis & Complications
EASL Studio Podcast S5 E11: The window hypothesis again, or just a closed window?

EASL Studio Podcast S5 E11: The window hypothesis again, or just a closed window?

Podcasts
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