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General Hepatology
EASL Studio Podcast S6 E14: Endohepatology: The endoscopic liver gold rush

EASL Studio Podcast S6 E14: Endohepatology: The endoscopic liver gold rush

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EASL Studio S6 E14: Endohepatology: The endoscopic liver gold rush

Description

This insightful discussion is centred on the burgeoning field of endohepatology, where advanced endoscopic techniques revolutionise hepatology practice. With this episode, explore the broad scope of endoscopic procedures (including EUS-guided liver biopsy, portal pressure measurement, and gastric varices embolisation) and their transformative impact on diagnostics and therapeutic interventions in liver disease.

To learn even more about endoscopic procedures in hepatology, take a look at this study by Wim Laleman et al., published in January 2024 in the Journal of Hepatology.

Faculty 

  • Wim Laleman (Moderator)
  • Andres Cardenas (Faculty)
  • Gavin Johnson (Faculty)
  • Reem Sharaiha (Faculty)

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ℹ️ Please click here to access the podcast version of this EASL Studio episode.

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General Hepatology
EASL Studio Podcast S6 E12: Do we care enough about the importance of DILI/DHILI ?

EASL Studio Podcast S6 E12: Do we care enough about the importance of DILI/DHILI ?

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EASL Policy Dialogues S3 E3: EASL’s statement: Key asks to the EU for the liver

Description

In April 2024, EASL released a statement to reiterate evidence-based recommendations to the European Union Institutions for the next political term, to address boldly the human and financial burden of liver disease in Europe. Policy makers can no longer ignore the enormous impact on millions of lives across Europe, and on health budgets in every country.

The EASL Policy Dialogues Season 3 is supported by Novo Nordisk. EASL has received no input from Novo Nordisk with regards to the content of the EASL Policy Dialogues Season 3.

 

Speakers

 
Debbie Shawcross

Debbie Shawcross is a Clinician Scientist and Professor of Hepatology and Chronic Liver Failure at the Institute of Liver Studies and James Black Centre, King’s College London. She works as a Consultant Hepatologist on the King’s Liver Unit with a specialist interest in hepatic encephalopathy and the complications of cirrhosis. She was elected to the EASL Scientific Committee and Governing Board in October 2022 and is an advocate for high quality education and training in gastroenterology and hepatology having been a Health Education England London Gastroenterology Training Programme Director for 10 years serving on the British Society Gastroenterology (BSG) Specialist Advisory Committee and Training Committee, BSG Mentor and an active member of the BSG Supporting Women in Gastroenterology. She is Deputy Chair of the BSG Research Committee. Her research programme characterises the immunobiology of chronic liver failure focusing specifically on the gut-liver-brain axis in the context of the gut microbiome as a driver of immune dysfunction, inflammation and encephalopathy. She is leading the field in clinical trials of faecal microbiota transplantation (FMT) in Europe and is Chief Investigator of the NIHR-funded EME UK multicentre randomised placebo-controlled clinical trial of FMT (capsules) [PROMISE Trial] in patients with metabolic-associated and alcohol-related cirrhosis.

Joern Schattenberg

Jörn M. Schattenberg is a Professor of Medicine and Director of the Department of Medicine II at the University Medical Center Homburg and University of the Saarland in Germany. He received his medical degree in 2002 after studying at the University of Mainz (Germany) and at the Tulane University in New Orleans (US). He completed his post-doctoral training at the Albert-Einstein College of Medicine, New York, where he focused on delineating signalling pathways involved in the pathophysiology of acute and chronic liver injury with a special focus on metabolic liver disease and non-alcoholic steatohepatitis (NASH). He is board-certified in Internal Medicine and Gastroenterology & Hepatology and Infectious Disease. His research focuses on translational sciences and clinical trials in Hepatology. He is involved in multinational, EU-funded research consortia exploring new technologies and approaches for the prevention and screening of metabolic liver disease and the development of novel biomarkers. Professor Schattenberg is member of the Policy, Public Health and Advocacy Committee of the European Association for the Study of the Liver (EASL), a member of the Editorial Board of Hepatology and the Alimentary Pharmacology & Therapeutics and an Associate Editor of JHEP Reports.

Frank Murray

Prof. Frank Murray is Consultant Hepatologist/Gastroenterologist at Beaumont Hospital, Dublin and Associate Professor of Medicine at the Royal College of Surgeons in Ireland and EASL Policy and Public Health Committee Member. He graduated from University College Dublin in 1980 and trained in Dublin, Boston USA, and Nottingham, England. He was previously Consultant Gastroenterologist in Ninewells Hospital and Medical School, Dundee, Scotland. Prof. Frank Murray became a a Fellow of the Royal College of Physicians of Ireland in 1994, was elected to the Council in 2002, and was appointed Registrar in 2007. He was the 141st President of the Royal College of Physicians of Ireland from 2014-2017. Prof. Murray is also the former chair of both the Basic Specialist Training Committee and the Irish Committee on Higher Medical Training. He is a founding member of the RCPI/HSE EQUALS Initiative, a group which sources decommissioned medical equipment in Irish hospitals to send to hospitals in less developed countries and is partnering the development of Post-graduate Training in Zambia. Prof. Murray is Chairman of the RCPI Policy Group on Alcohol in 2102 , and Chairman of Alcohol Health Alliance Ireland in 2015. He has played a prominent national role in highlighting alcohol harm in Ireland and supported the introduction of evidence-based alcohol counter-measures, such as those in the Public health Alcohol Bill. Prof. Murray has recently been appointed Director, National Doctors Training and Planning (NDTP), HSE in Dublin.

Loreta Kondili

Prof. Loreta Kondili is a specialist in Gastroenterology and Digestive Endoscopy since 2005 and earned her Ph.D. degree in 2015. She is trained in Sapienza University and Policlinico Umberto 1- Rome and in the Liver Unit of Queen Elisabeth Hospital/ University of Birmingham (UK). She is a Clinical Researcher at the Center for Global Health, Istituto Superiore di Sanità, Rome. Prof. Kondili has worked in viral hepatitis and liver diseases for the last 25 years, and her main research areas focus on epidemiological, clinical, and therapy of chronic viral liver disease. She has been involved in the scientific coordination of several Italian Networks in the field of chronic liver disease of different etiologies with specific regard to chronic viral hepatitis, liver cirrhosis, and its complications. She is currently the principal investigator of the Italian Platform for the study of Viral Hepatitis Therapies (PITER). She has strong competencies in the Health Technology Assessment and management and analysis of real-life big databases. She has collaborated with the Center for Economic and International Studies (CEIS) of the Tor Vergata University of Rome and the Center for Disease Analysis Colorado (USA), for the definition of the HCV elimination strategies in Italy as a goal of the World Health Organization. She is currently serving as expert for the Italian Ministry of Health on the implementation of the National Hepatitis plan. She has been an expert of the Italian Drug Agency (AIFA) and is currently serving as expert at European Medicines Agency (EMA) She is a Professor of Medicine at the University of Tirana. She passed the National Scientific Qualification as Associated Professor (Bando D.D. 1532/2016 Settore concorsuale 06/D4 Fascia: II). She holds a 2nd level master’s in Evaluation and Management of Health Technologies from the Catholic University of Rome. She is a member of the Italian Association for the Study of the Liver and of the European Association for the Study of the Liver (EASL) serving also as a member of the Policy and Public Health Committee of EASL. Prof Kondili has co-authored over 100 publications on hepatitis and is a frequent speaker in national and international scientific meetings.

Peter Jepsen

Born in 1975, graduated from the medical school in Aarhus, Denmark in 2003. Since then clinical training and specialisation in hepatology, alongside training in clinical epidemiology. I have published more than 100 papers, most of them in the field of hepato-epidemiology. I currently do half-time clinical work, half-time research. My primary interests are alcoholic liver disease and hepatocellular carcinoma, most notably the value of surveillance for hepatocellular carcinoma among patients with alcoholic cirrhosis.

 

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EASL Studio S6 E13: Resmetirom: First approved drug for MASH, for whom and for how long?

Description

This episode explores the approval of resmetirom for NASH, analysing its integration into clinical practice and patient eligibility. The experts also discuss the role of lifestyle interventions alongside resmetirom, the use of biomarkers for patient selection, treatment monitoring, and the expected landscape changes over the next five years.

Faculty

  • Aleksander Krag (Moderator)
  • Naim Alkhouri (Faculty)
  • Sven Francque (Faculty)
  • Amalia Gastaldelli (Faculty)

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ℹ️ Please click here to access the podcast version of this EASL Studio episode.

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Viral Hepatitis
Quiz: A 38-year-old man presents with Chronic Hepatitis D.

Quiz: A 38-year-old man presents with Chronic Hepatitis D.

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Viral Hepatitis
EASL Clinical Practice Guidelines on hepatitis delta virus

EASL Clinical Practice Guidelines on hepatitis delta virus

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Metabolism, Alcohol & Toxicity
EASL Studio Podcast S6 E13: Resmetirom: First approved drug for MASH, for whom and for how long?

EASL Studio Podcast S6 E13: Resmetirom: First approved drug for MASH, for whom and for how long?

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EASL Studio S6 E12: Do we care enough about the importance of DILI/DHILI ?

Description

Join us for a critical discussion on the significance of Drug and Herbal & Dietary Supplement-Induced Liver Injury (DHILI). In this episode, the speakers explore the importance of DHILI, assess recent advancements, and deliberate on the obstacles hindering further progress in addressing this pressing healthcare concern.

This episode is organised in collaboration with the EASL DHILI Consortium.

Faculty

  • Guruprasad Padur Aithal (Moderator)
  • Paul Hayashi (Faculty)
  • Maribel Lucena (Faculty)
  • Paul Watkins (Faculty)

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ℹ️ Please click here to access the podcast version of this EASL Studio episode.

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EASL Studio S4 E4: JHEP Live: Is the term ‘decompensated cirrhosis’ outdated?

Description

Although there is an almost unanimous consensus on the prognostic weight of the term ‘decompensation’, a clear corresponding consensus on its definition is still lacking. In addition, classifying cirrhosis as compensated and decompensated oversimplifies the clinical course of the disease which encompasses many different groups.

Faculty

  • Prof. Paolo Angeli (Moderator)
  • Prof. Guadalupe Garcia-Tsao (Faculty)
  • Prof. Salvatore Piano (Faculty)
  • Prof. Thomas Reiberger (Faculty)

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

 

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EASL Studio S2 E4: Betablockers in cirrhosis: Has Baveno consensus gone too far?

Description

The Baveno Consensus started over 30 years ago with the aim of reviewing current diagnostic and therapeutic strategies and producing updated definitions.

But, with the extension of indication of non-steroidal beta blockers, has the consensus gone too far?

  • Is there enough evidence for their use in already decompensated patients?
  • How safe are they in this patient population?
  • What do we know about the effects on refractory ascites? Circulatory dysfunction?

ℹ️ Please click here to access the podcast version of this EASL Studio episode.

 

Moderator

 
a. krag Aleksander Krag is Professor and Head of Hepatology at University of Southern Denmark and Odense University Hospital. Main research areas are within complications to cirrhosis, portal hypertension and alcoholic liver disease. He is involved in a number of collaborations, including being Coordinator in the H2020 project GALAXY: Gut and liver axis in alcoholic liver fibrosis.

Faculty

 
Thomas REIBERGER

Thomas Reiberger is a hepatologist at the Medical University of Vienna focusing on translational research in the field of advanced chronic liver disease. His Christian-Doppler Laboratory for Portal Hypertension and Liver Fibrosis deciphers molecular mechanisms involved in fibrogenesis and fibrosis regression and evaluates novel treatment options for portal hypertension and antifibrotic therapies in preclinical studies. As a physician, he heads the liver outpatient clinic, the Ultrasound/Elastography unit and the post liver transplant care at the Medical University of Vienna. Currently, he also serves as the Scientific Secretary of the Baveno Cooperation.

Dominique Thabut

Dominique Thabut is Professor in Hepatology at the APHP Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France. Her areas of expertise include end-stage liver diseases, portal hypertension, hepatic encephalopathy. She participated in the development of the portal hypertension and hepatic encephalopathy international guidelines (Baveno, EASL, AASLD).

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EASL Studio S6 E11: Assessment of clinically significant portal hypertension in 2024 – Is it time to say goodbye to invasive measurements?

Description

In this episode, experts explore the shift away from invasive measurements in assessing clinically significant portal hypertension. The speakers address the crucial data needed to enhance the reliability and applicability of these non-invasive methods and introduce several advanced elastography techniques, shaping the future of portal hypertension assessment.

Faculty

  • Bogdan Procopet (Moderator)
  • Maria Papp (Faculty)
  • Atoosa Rabiee (Faculty)
  • Thomas Reiberger (Faculty)

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ℹ️ Please click here to access the podcast version of this EASL Studio episode.

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