Chasing the perfect SLD preclinical model

 

 

 

Steatotic liver disease (SLD) research relies heavily on preclinical models, yet no single model can fully capture the complexity of human disease. In this episode, we explore the new EASL position paper on preclinical SLD models. From MASLD and MetALD to organoids and precision-cut liver slices, we discuss the strengths, limitations, and translational relevance of today's most widely used models. How do we choose the right model, and are we any closer to finding the perfect one?

Based on EASL position paper on preclinical models of steatotic liver disease

Host: Rui Castro (University of Lisbon) 
Speakers: Mathias Heikenwälder (University of Tübingen) and Suchira Gallage (University of Tübingen)

Prefer to listen on the go? This episode is also available on the following streaming platforms:

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Talk Liver To Me is supported by Opella. Opella has had no input to the content of this programme. 

This programme is intended for health are professionals only and is provided for educational purposes. EASL does not endorse or promote any medicinal products or medical devices. The views and opinions expressed are those of the speakers and do not necessarily reflect those of EASL. 

COI:

  • Rui Castro has no potential conflicts of interest to disclose. 
  • Suchira Gallage and Mathias Heikenwälder have disclosed the following potential conflicts of interest: Research collaboration with OrsoBio.

EASL is not responsible for the accuracy of any translated versions of this podcast or of subtitles generated automatically by artificial intelligence.

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