Description

In this JHEP Live the faculty discuss the use of antisense oligonucleotides and siRNAs in the treatment of chronic hepatitis B infections.

Faculty

• Prof. Joerg Petersen (Moderator)
• Prof. Maria Buti (Faculty)
• Prof. Man-Fung Yuen (Faculty)

Articles of interest

• Combination treatments including the small-interfering RNA JNJ-3989 induce rapid and sometimes prolonged viral responses in patients with CHB
• N-acetyl galactosamine-conjugated antisense oligonucleotide (GSK3389404) in chronic hepatitis B patients on stable nucleos(t)ide therapy: Phase 2a, randomised, double-blind, controlled study

Related episodes

• Treatment of HBV-HDV coinfection in the era of entry inhibition
• JHEP Live: Stop Nuc in HBeAg negative patients
• Midday Talks: HBV and HDV drug development – Where do we stand and where are we going?

ℹ️ Please click here to access the podcast version of this EASL Studio episode.