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HCC is the most common primary liver cancer and often develops in the setting of chronic liver disease. Early detection of HCC through surveillance allows for timely intervention and improved patient outcomes.

Which of the following patients should have surveillance for hepatocellular carcinoma?

A. A 42-year-old lady with a past history of non-cirrhotic chronic hepatitis C, cured by direct acting antiviral therapy

B. A 59-year-old man with alcohol induced cirrhosis (jaundiced, albumin 27g/dl; prothrombin time 21 seconds, ascites managed on diuretics), who still drinks two-three glasses of wine each night

C. A 64-year-old man with NAFLD, with a BMI of 34 and stage 2 fibrosis on liver biopsy

D. A 64-year-old man with non-cirrhotic hepatitis B and a platelet count of 160,000/µl

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