EASL Campus

A 57-year-old male liver donor is offered for allocation with the following medical characteristics: ALT 56 U/L, AST 53 U/L, GGT 98 U/L, ALP 124 U/L, bilirubin 22 µmol/L, albumin 42 g/L, INR 1.1. Abdominal CT shows a liver of normal morphology without focal lesions. Medical history reveals prostate cancer (Gleason score 3+3) and confirmed HCV infection with HCV RNA PCR of 7 million copies.

Which of the following statements is correct?

A. This donor is absolutely contraindicated due to a history of prostate cancer.

B. Mildly elevated liver enzymes alone represent an absolute contraindication for liver donation.

C. The presence of active HCV infection precludes use of the graft in any recipient.

D. This donor may be considered for transplantation, but only in HCV-positive recipient

E. This donor may be considered for transplantation in an HCV-negative recipient, provided that informed consent is obtained, organ quality is appropriate, and rapid initiation of effective antiviral therapy is ensured.

Community Stream

Easl Community Feed My Feed