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Fibrosis is the most important prognostic factor in NAFLD, correlating with liver-related outcomes and mortality. For this reason, the presence of advanced fibrosis is of paramount importance during investigations for NAFLD.

Which of the following affirmations is correct?

A. Advanced fibrosis or cirrhosis needs to be confirmed by liver biopsy

B. Bariatric surgery is effective in NAFLD-associated liver injury, improving necroinflammation but not fibrosis

C. Biomarkers and scores of fibrosis, as well as transient elastography, are acceptable and accurate non-invasive procedures for the identification of cases at high risk of advanced fibrosis/cirrhosis

D. Diet and exercise training reduce steatosis, ballooning, inflammation and fibrosis in both children and adults

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